A Total Stomach Method for Estimating Acute Food Comsumption by Diazepam in Rats

Abstract

Acute increase in food consuming of rats by diazepam was quantitatively analysed by measuring total stomach weight including the weight of food intaken. The Methodological details of stomach weight measurement were described in this paper. Though present method has disadvantage of inevitable sacrifice of the animals, it seemed suitable for the analysis of acute polyphagic effect of diazepam in that future chemical analysis of neurotransmitters in hypothalamus is necessary for the study of mechanism of polyphagic effect of diazepam.