1986 Volume 17 Issue 4 Pages 539-545
Identical twins, 23 years in age, were seen to our clinic with chief complaints of multiple tumor nodes palpable in the right breast. When the older and younger sister were examined in 1984, three tumor nodes were found in the right breast with a maximal diameter of 5.2cm and 5.5cm for each case. Under the diagnosis of fibroadenomata, tumor resectomies were done when the pathological diagnosis of fibroadenoma and/or fibroadenoma with tubular adenoma were given. Borderline malignancy was identified in the tumor nodes of the older sister. The sisters were confirmed as the identical twins by means of HLA analysis and blood typing. This gives us a suggestion that the genetic factors should be considered as a cause for the development of neoplasm, especially in case of fibroadenoma mammae.