Prediction of outcome of pregnancy in threatened abortion

Abstract

Fifty-three cases of threatened abortion were studied and followed up to determine the value of immunoassay method of human chorionic gonadotropin (HCG) and a vaginal cytology in assessing the prognosis with regard to the outcome of pregnancy. The semi-quantitative estimation of HCG titers was found to be of great prognostic significance. Patients who had high titers more than 8 times dilution of urine showed good outcome and those who had low titers less than 4 times dilution aborted. The karyopyknotic index (PI) of vaginal cytology had also prognostic value in threatened abortion. Patients who showed higher PI than 20∿25% in vaginal cytology all aborted few days later. The combination of these two techniques will increase the reliability and accuracy in predicting outcome of pregnancy in threatened abortion.