2006 Volume 37 Issue 1-2 Pages 8-15
It is possible to enforce medical treatment efficiently to the suitable case for an early stage, if the poor prognosis group which is likely to carry out lymph node metastasis of a biopsy can be sorted out. In this study, the expression of VEGF-C which was related to lymphangiogenesis was examined on VEGF-C expression and lymphatic vessel invasion in the breast cancer tissues. As the result, the breast carcinoma cell of the VEGF-C positive expression was confirmed in many lymphatic vessel invasion example, and the significant differential was between VEGF-C expression and lymphatic vessel invasion (p<0.001). It was suggested that VEGF-C in which the breast cancer tissues was produced became an useful factor which can predict the lymph node metastasis from the case without lymphatic vessel invasion and lymph node metastasis.
