2023 Volume 54 Issue 2 Pages 41-47
We report a 6-year-old girl with atopic dermatitis who developed eczema coxsackium caused by coxsackievirus A6 (CVA6) . At the time of her initial diagnosis, based on her medical history and clinical symptoms, we considered her to have Kaposi's varicella-like rash (eczema herpeticum) caused by herpes simplex virus (HSV) and started her on acyclovir, but later found that her serum HSV antibody titer was negative and CVA6 antibody titer was positive on admission. Although eczema herpeticum often presents with corneal and periocular symptoms, no periocular skin rash was seen in this case. If the periocular rash is not severe, a viral infection other than HSV may be suspected, and searching for the causative virus, including CVA6, may help in the diagnosis.