Koutou (THE LARYNX JAPAN)
Online ISSN : 2185-4696
Print ISSN : 0915-6127
ISSN-L : 0915-6127
Case Reports
Advanced Laryngeal Cancer Treated by Intra-arterial Chemoradiotherapy after Neck Dissection: A Case Report
Hiroyuki MihashiSyunichi ChitoseAkiteru MaedaHirohito UmenoTadashi Nakashima
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2010 Volume 22 Issue 2 Pages 128-131

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Abstract
The effectiveness of intra-arterial chemoradiotherapy (IACRT) against advanced laryngeal cancer has recently been reported. Yet, the indication of IACRT in cases with neck lymph node metastasis has not been discussed. Although planned neck dissection after radiotherapy is performed at many institutions, the radiotherapy often cause unfavorable postoperative complications. We treated a 57-year-old male, whose chief complaint was hoarseness, at our university hospital. Fiberoptic examination revealed an irregular tumor on the right subglottic lesion extending to the right ventricle. Images from computed tomography suggested the presence of metastatic cervical lymph nodes. Subglottic squamous cell carcinoma of the larynx (T2N2bM0) was histologically diagnosed. As a treatment, selective neck dissection for the cervical metastasis was first performed. During surgery, the supra-and inferior-thyroidal arteries were preserved. Ten days after the surgery, IACRT for the local tumor was given every other week using the supra-thyroidal artery. The IACRT was continued for five weeks and, as a result, the tumor has completely disappeared. The patient has been free from recurrence for more than a year.
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© 2010 The Japan Laryngological Association
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