2018 Volume 30 Issue 2 Pages 122-125
Spontaneous regression of a malignant tumor is rare, and that of laryngeal cancer is extremely rare. We herein report a case of laryngeal cancer with spontaneous regression.
A 43-year-old man presented to our hospital with a four-week history of hoarseness. An endoscopic examination revealed an irregular tumor in his left vocal cord. After an endoscopic biopsy and computed tomography, he was diagnosed with laryngeal squamous cell carcinoma (cT1aN0M0). Before starting radiation therapy, his hoarseness improved, and the cancer disappeared without any treatment. The clinical course was uneventful, and there has been no recurrence in the 30 months since his first visit.
It is speculated that the endoscopic biopsy may have triggered the spontaneous regression of his laryngeal cancer, although the associated mechanism is unclear.