Abstract
A case with juvenile laryngeal papilloma manifesting malignant change in excrescence was reported. This patient had suffered from dyspnea since 1955, when he was one years old. A huge tumor occupied the larynx and trachea, and the pathological diagnosis was papilloma. He underwent laryngomicrosurgery using CO2 laser many times at a neighboring hospital. Although the pathological diagnosis of papilloma was determined upon the first visit to our hospital, the tumor enlarged quickly after a month. Since his final histological diagnosis was squamous cell carcinoma, he underwent total laryngectomy and partial pharyngo-esophagectomy for radical treatment, followed by radiotherapy (60Gy). Some discussions were made concerning the malignant transformation, etiology and treatment of papilloma.
