Abstract
Viscoelastic properties of the lamina propria of human adult vocal fold mucosa are essential for vibrating behavior. These viscoelastic properties depend upon the three-dimensional structure of the extracellular matrices.
The complex of extracellular matrices is very important for the viscoelastic properties of the human adult vocal fold mucosa. Geriatric changes of each extracellular matrix and its threedimentional structure of the human adult vocal fold mucosa changed the structure and viscoelasticity of the human vocal fold mucosa as a vibrating tissue, and thus is one of the causes of geriatric changes of voice. Macula flavae of human vocal folds are involved in the metabolism of extracellular matrices and their geriatric changes.