Two Cases of Neuroendocrine Carcinoma of the Epiglottis

Abstract

Neuroendocrine carcinoma is an uncommon disease in the larynx. We had two cases of laryngeal neuroendocrine carcinoma. Both patients had a laryngeal tumor in the epiglottis.
Case 1, a 55-year-old male, was diagnosed with small cell carcinoma according to light microscopic and immunohistochemical findings. Because he did not have cervical neck metastasis, he was treated with a partial laryngectomy and postoperative radiotherapy. When postoperative cervical metastasis occurred after initial treatment, he underwent radical neck dissection. He died of multiple bone metastasis 2 years after diagnosis. Case 2, a 68-year-old female, was diagnosed with an atypical carcinoid. She was treated with a horizontal partial laryngectomy. She is alive without recurrence 21 months after the operation.