Abstract
Two handred and eighty two cases of laryngeal carcinoma treated for the past 15 years in the University of Tokyo were reviewed. During the first five years a combination of repeated mass-reduction surgeries and small-dose radiotherapy was employed. The 5-year survival rate was 53% and the 5-year local no-recurrence rate of Tla glottic carcinomas was 59%. During the following four years a radical radiotherapy (50 Gy in total) was applied for all cases. Salvage operation was conducted for failures. The 5-year survival rate was 58% and the 5-year local no-recurrence rate of Tla glottic carcinoma was 50%. During the latest six years a radical radiotherapy (60 Gy or more in total) was indicated to early cases and radical surgical therapy was conducted for advanced cases. The 5-year survival rate was 85% and the 5-year local no-recurrence rate of Tla glottic carcinomas treated with radiotherapy was 83 %. When the radical radiotherapy was combined with a pre-radiation mass-reduction procedure, 95% of Tla glottic carcinoma was controlled. Laser in useful to the mass reduction procedure.
