Abstract
During the period from 1981 to 1989, a total of 52 patients with T1 glottic laryngeal cancer (40 patients of T1a and 12 of T1b) received definitive irradiation therapy in our clinic. In 7 patients, residual tumor was recognized histologically by microscopic biopsy 2 to 3 weeks after radiation therapy. Of these 7 patients, 4 were treated by laser surgery and 2 underwent total laryngectomy. One patient refused further treatment but he is still alive without any sign of recurrence. On the other hand 5 patients developed local recurrence following irradiation therapy. Four of the 5 patients underwent total laryngectomy and the other received additional irradiation. The median interval to the local recurrence was 18 months (ranging from 10 to 28 months). The final local control rate for the present series was 96.1% and voice preservation rate was 88.5%.
