1997 Volume 9 Issue 2 Pages 167-169
A 67-year-old man, who had been treated for hypertension by Angiotensin converting enzyme (ACE) inhibitor therapy for 8 years, complained of difficulties in voice phonation for 3 years. He also complained of dry cough after the administration of ACE inhibitor therapy. Under indirect laryngoscopy, a granuloma with ulceration was observed in the right arytenoid area.
Dry cough was one of the unfavorable side effects of ACE inhibitor therapy, so we thought that the long-lasting dry cough caused the laryngeal granuloma. Then, we changed the prescription from ACE inhibitor to another anti-hypertension drug. Two days later, the dry cough had improved dramatically and the laryngeal granuloma completely disappeared after 16 weeks.
