Abstract
Acute amebic appendicitis, a rare presentation of Entamoeba histolytica infection, is challenging to distinguish from non-amebic appendicitis because of similarities in symptoms and laboratory data. Here, we describe the case of a 42-year-old Japanese male with amebic appendicitis diagnosed by histopathological examination of the removed appendiceal specimens. In this case, blood eosinophilia was not observed, and amebic trophozoites were histologically distributed not only in surface exudates but also in appendiceal submucosa and muscularis propria. In addition, a thorough interview and additional colonoscopy after the diagnosis revealed a history of amebic colitis and persistent amebic colitis. We believe that physicians should be aware of the possible presence of amebic appendicitis because of its higher mortality rate compared to non-amebic appendicitis.
