The Review of Laser Engineering
Online ISSN : 1349-6603
Print ISSN : 0387-0200
ISSN-L : 0387-0200
In Vivo Spectroscopic Imaging of Caenorhabditis Elegans
Shinichi MIYAZAKIv HAYASHIHideaki KANO
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2021 Volume 49 Issue 5 Pages 276-

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Abstract

Spectroscopic imaging unveils what kinds of biomolecules exist in cells, tissues, or animals. Coherent anti-Stokes Raman scattering (CARS) spectroscopic imaging enables us to obtain molecular information in a living model organism, Caenorhabditis elegans. The microspectroscopic system employs a new laser source based on the dual-fiber-output configuration, which generates 50-ps laser pulses with 1 MHz repetition rate. The system enables us to conduct label-free spectroscopic imaging in vivo. Spectroscopic imaging has the potential to uncover crucial questions in life sciences.

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© 2021 by The Laser Society of Japan
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