GENETIC STUDIES ON THE KANAMYCIN RESISTANCE SYSTEM OF MYCOBACTERIUM AVIUM

Abstract

Genetic studies have been made on the kanamycin resistance system of Mycobacterium avium, R-type Jucho strain, by population analysis method. It has been indicated that kanamycin resistance system of Mycobacterium avium has multiple genotypes. It has been suggested that there are multiple genes, each of which is instrumental for kanamycin resistance but differs in their potency. It is notewothy that the range of resistance development of this organism is very narrow, unlike the case of M. tuberculosis.