MICROBIOLOGY and IMMUNOLOGY
Online ISSN : 1348-0421
Print ISSN : 0385-5600
ISSN-L : 0385-5600
Identification of Influenza C Virus Phosphoproteins
Hidekazu NishimuraKanetsu SugawaraPeng GaoYasushi MurakiSeiji HongoFumio KitameKiyoto Nakamura
Author information
JOURNAL FREE ACCESS

1995 Volume 39 Issue 9 Pages 737-740

Details
Abstract
The HMV-II cells infected with influenza C virus were labeled with inorganic [32P]phosphate to identify phosphorylated proteins. Analysis by radioimmunoprecipitation with antiviral serum or monoclonal antibodies revealed that three major structural proteins of the virus, hemagglutinin-esterase (HE), nucleoprotein (NP), and matrix protein (M1) are all phosphorylated in both infected cells and virions. It was also observed that, in the presence of trypsin (10μg/ml), the unphosphorylated form of the HE glycoprotein was cleaved efficiently whereas the phosphorylated form was not, raising the possibility that phosphorylation of HE may influence its susceptibility to degradation by proteolytic enzymes.
Content from these authors
© Center for Academic Publications Japan
Previous article
feedback
Top