Development of a Two-Dimensional Mass Spectrometer Using an Axially Resonant Excitation Linear Ion Trap

Abstract

We performed a preliminary study on two-dimensional mass spectrometry (1st dimension, precursor ion's m/z; 2nd dimension, fragment ion's m/z) using an axially resonant excitation linear ion trap (AREX LIT) as the source ion trap. The spectrometer, consisting of a source ion trap with mass selectivity, a collision cell, and mass analyzer, is expected to have a duty cycle over 40 times that of conventional tandem mass spectrometers. Because the AREX LIT can eject ions with an efficiency of over 70% and energy dispersion of only a few electron volts, it can obtain a 2D mass spectrum with a good S/N in only 1 s.