Mass Spectra of 2-Thioxo-Pyrimidine Derivatives

Hiroshi Kishi; Satoshi Kambe

doi:10.5702/massspec1953.27.83

Hiroshi Kishi, Satoshi Kambe

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Keywords: 2-Thioxo-pyrimidine derivatives, Mass spectrometry, Fragmentation mechanism

JOURNAL FREE ACCESS

1979 Volume 27 Issue 2 Pages 83-95

DOI https://doi.org/10.5702/massspec1953.27.83

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Published: June 30, 1979 Received: December 25, 1978 Available on J-STAGE: June 28, 2010 Accepted: - Advance online publication: - Revised: -
Correction information
Date of correction: June 28, 2010 Reason for correction: - Correction: DTRECEIVED Details: Right : 19781225

Date of correction: June 28, 2010 Reason for correction: - Correction: AFFILIATION Details: Wrong :
1) Oyama Technical College, Oyama-shi, Tochigi, 323, Japan.

Right :
1) Oyama Technical College,

Date of correction: June 28, 2010 Reason for correction: - Correction: KEYWORD Details: Wrong : 2-Thioxo-pyrimidine derivatives Mass spectrometry Fragmentation mechanism
Right : 2-Thioxo-pyrimidine derivatives, Mass spectrometry, Fragmentation mechanism

Date of correction: June 28, 2010 Reason for correction: - Correction: CITATION Details: Wrong : E
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Abstract

Mass spectra of 2-thioxo-pyrimidine derivatives were measured and their fragmentation mechanisms were elucidated with the aid of the shift of peaks by substituents and by the deuterium labeling, and with the aid of metastable peaks. Samples tested were(1)6-alkyl or aryl-5-cyano-4-oxo-2-thioxo-1, 2, 3, 4-tetrahydropyrimidine derivatives, (2)6-alkyl or aryl-5-cyano-2, 4-dioxo-1, 2, 3, 4-tetrahydropyrimidine derivativees, (3)6-aryl-4-imino-5-cyano-2-thioxo-1, 2, 3, 4-tetrahydropyrimidine derivatives, (4)6-alkyl or aryl-5-cyano-4-oxo-2-thioxo-1, 2, 3, 4, 5, 6-hexahydropyrimidine derivatives. The characterisitic fragmentation for the 1, 2, 3, 4-tetrahydropyrimidine derivatives was RDA-cleavage. The 4-imino-substituent complicated the fragmentation mechanisms. 1, 2, 3, 4, 5, 6-Hexahydropyrimidinederivatives showed mass spectra quite different from those of 1, 2, 3, 4-tetrahydropyrimidines.

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