Abstract
A 18-year-old female high school student visited our hospital with complaints of a sustained fever ranging between 39℃ and 40℃. She had stayed for one week at a hotel in Osaka in February 2008. She had never been abroad in her life. At the time of her first visit, we diagnosed that she might be suffering from some type of acute viral infection and admitted her to the hospital for medical observation. Blistering fever continued in spite of antibiotics medication, we did two sets of blood culture tests following upon a 48 hours’ interruption of the antibiotics therapy. The sample of one blood culture proved the presence of Salmonella Typhi. We administered the Pazufloxacin antibiotic drug intravenously for three days and the Levofloxacin orally for two weeks. She began to feel better after the treatment and it was determined that she no longer carried any typhoid bacteria after a double stool culture test. In Japan, from 50 to 80 cases of typhoid fever occur each year, and about 80% of these are acquired while traveling abroad. Because cases of typhoid fever are currently uncommon in Japan, we report this domestic case of typhoid fever at our hospital.
