A Case of Giant Meningioma presenting Depression.

Abstract

We report the case of a 41-year-old man who was initially thought to have depression, but was eventually diagnosed with frontal lobe syndrome caused by a giant frontal parasagittal meningioma. As Tumor resection lead remission of depression, the symptom had been caused by the compression of the dorsal lateral prefrontal cortex (DLPFC). Recently hypoactivity of DLPFC has been noted in major depressive disease. We discuss the phenomenon of this patient from the neuroscientific point of view.