Abstract
Ki-67 index is widely used for benign-malignant discrimination, diagnosis of the malignancy, and prognosis. We propose and develop a nuclear analysis system for the immunohistochemical staining image. In our method of Whole Slide Image (WSI) analysis, the region for the analysis is automatically selected and no individual conditionalization for each image pattern is necessary. There is a high correlation between Ki-67 index computed by our system and that by a visual count, indicating validity of our method.