Medical Imaging Technology
Online ISSN : 2185-3193
Print ISSN : 0288-450X
ISSN-L : 0288-450X
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Development of Fully Automatic Image Analysis System for Quantitation of Ki-67 Staining in Breast Cancer
Yoshiko YAMASHITATomoharu KIYUNAMasahiro YAMAGUCHI
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JOURNAL FREE ACCESS

2015 Volume 33 Issue 3 Pages 124-132

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Abstract
Ki-67 index is widely used for benign-malignant discrimination, diagnosis of the malignancy, and prognosis. We propose and develop a nuclear analysis system for the immunohistochemical staining image. In our method of Whole Slide Image (WSI) analysis, the region for the analysis is automatically selected and no individual conditionalization for each image pattern is necessary. There is a high correlation between Ki-67 index computed by our system and that by a visual count, indicating validity of our method.
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© 2015 The Japanese Society of Medical Imaging Technology
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