Intravital Imaging of Cancer Cell Dynamics

Abstract

Recently, it has been important to understand the tumor microenvironment for invasion and metastasis of cancer. We could analyze the cancer cell dynamics multi-dimensionally by intravital imaging without disturbing their microenvironment. Therefore, many attempts have been made to understand the behavior of cancer cells together with their microenvironment using this technique and to clarify the related molecules and pathology. Here we present our latest data on cancer cell dynamics, and discuss the applications of this novel methodology for future studied in the field of cancer.