Abstract
Alzheimer's disease is the most cases in dementia, and a diagnosis for its very early stage is required. A deposit of amyloid beta (Aβ) is recognized to cause Alzheimer's disease, and it can be visualized using PET, an amyloid imaging. An amyloid imaging therefore promises a useful tool for Alzheimer's diagnosis. A highly quantitative measurement of Aβ deposit is required for an effective diagnosis to Alzheimer's disease with PET, and thus, this article aims to survey some aspects in an amyloid imaging: the theory to quantify amyloid deposit using PET, a necessity of a dynamic PET study that acquired a time history of radioactivity in tissues with multiple PET scans, and a method of early images to reduce an issue of a total PET scan time.
