2021 Volume 39 Issue 5 Pages 199-205
WGI is a new imaging technique for nuclear medicine diagnosis based on the concept of “utilizing all detectable gamma rays for imaging”. Adding Compton camera function to PET enables to use radionuclides that have not been widely used for imaging. In order to realize the full potential of WGI, the key point is to improve the performance of the scatterer detector ring, which is inserted into the PET detector ring. The first half of this paper focuses on the principle of WGI and the development of the scatterer detector and the prototype for the proof of concept. The second half of this paper introduces the applications of WGI, such as new imaging methods that effectively utilize radionuclides such as 89Zr and 44Sc, which emit high energy gamma rays in addition to positron emission, and C-type Compton PET, which has the potential to upgrade existing MRI to PET/MRI.