Magnetic Resonance Spectra of Hyperpolarized ¹²⁹Xe in Human Blood and Living Rat Chest

Abstract

We constructed a gas polarization system to test the feasibility of using hyperpolarized ¹²⁹Xe gas as an NMR (nuclear magnetic resonance) probe to explore brain function. Both in vitro and in vivo experiments were performed with a 4.7T NMR spectrometer. Xenon spectra from human blood confirmed the existence of two peaks corresponding to red blood cells and plasma. In rat studies, three peaks at around 200 ppm were observed. Our results are consistent with previously reported data.