Magnetic Resonance in Medical Sciences
Online ISSN : 1880-2206
Print ISSN : 1347-3182
ISSN-L : 1347-3182
MAJOR PAPER
Simple Frame-based Approach for MR Imaging-guided Abdominal Biopsy: Preliminary Evaluation in a Phantom Model
Anastasia Antoniou, Nikolas Evripidou, Leonidas Georgiou, Antreas Chrysanthou, Antonis Christofi, Cleanthis Ioannides, Liyang Yu, Christakis Damianou
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JOURNAL OPEN ACCESS

2026 Volume 25 Issue 1 Article ID: mp.2024-0187

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Abstract

Purpose: Although automation offers several benefits in MRI-guided abdominal biopsies, the conventional surgeon-centric approach continues to be the preferred technique. This study presents an ergonomic biopsy device aimed at streamlining the MRI-guided abdominal biopsy process while preserving operator control.

Methods: A dedicated belt was designed with adjustable straps to accommodate patients of varying sizes. A biopsy frame with 2 manual degrees of freedom was movably affixed to the belt, allowing for adjustable positioning across the patient’s circumference to align with the region of interest. Preliminary testing was performed on an abdominal biopsy phantom with 2 embedded 7-mm tumor mimics in a 3T MRI scanner. Needle guide registration in MRI coordinates was achieved by attaching a water-filled syringe to the guide, which was then navigated to align with each target using a straightforward method involving the acquisition and fusion of parallel images. A clinically relevant half-Fourier acquisition single-shot turbo spin echo sequence was used for both the initial alignment and for intermittent imaging during the stepwise advancement of a metallic clinical needle toward the target.

Results: The device was easy to use, even for a non-experienced operator. The employed methodology enabled straightforward calculation of the 2D path for aligning the syringe with the target. Alignment accuracy was within the submillimeter range. The employed sequence was robust against susceptibility artifacts, enabling precise guidance, with the accuracy of tumor puncture ultimately dependent on the operator.

Conclusion: The proposed biopsy method has the potential to enhance stability and accuracy over traditional techniques, while being more ergonomic and cost-effective than advanced robotic systems, also maintaining human control. Extensive preclinical and clinical evaluation is needed to fully assess effectiveness and safety.

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© 2026 by Japanese Society for Magnetic Resonance in Medicine

This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.
https://creativecommons.org/licenses/by-nc-nd/4.0/
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