Abstract
A suspension of core-shell particles composed of a biodegradable polymer core and iron oxide nanoparticles (IONPs) exhibits higher heat generation under an alternating magnetic field compared with a suspension of IONPs at the same IONP concentration. The improvement of the heat generation will be attributed to the change of the strength of dipolar interactions between adjacent IONPs. The IONPs in the core-shell particles were relatively isolated, in contrast with that in IONP suspension before the formation of the core-shell particles. Therefore, in the core-shell particles, the dipolar interaction is reduced, and the heat-generating capability is increased. This explanation is brought through investigating the influence of the agglomerate size of IONPs on the heat-generating capability.