Rubratoxin B induces apoptosis in p53-null cells

Hitoshi NAGASHIMA; Yasuki ISHIZAKI; Masamichi NISHIDA; Ikuo MORITA; Sei-itsu MUROTA; Tetsuhisa GOTO

doi:10.2520/myco1975.1998.35

Hitoshi NAGASHIMA, Yasuki ISHIZAKI, Masamichi NISHIDA, Ikuo MORITA, Sei-itsu MUROTA, Tetsuhisa GOTO

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Keywords: rubratoxin B, apoptosis, p53, p53

JOURNAL FREE ACCESS

1998 Volume 1998 Issue 46 Pages 35-37

DOI https://doi.org/10.2520/myco1975.1998.35

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Abstract

Exposure to rubratoxin B caused homozygous null p53 cells to shrink, condense their chromo-somes and fragment their nuclei, showing that rubratoxin B induces apoptosis in p53-null cells

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