Nano Biomedicine
Online ISSN : 2185-4734
Print ISSN : 1883-5198
ISSN-L : 1883-5198
MINI REVIEW
Study of Cytotoxicity Level by Combining Nanomaterials and Chemical Substances Dissolved in Culture Medium
Tsubasa SHIRAIYoshiya HASHIMOTOKoichi IMAI
Author information
JOURNALS FREE ACCESS

2020 Volume 12 Issue 2 Pages 120-124

Details
Abstract

Nanomaterials may be combined in many dental component materials in the future. Moreover, products prepared with nanomaterials alone are rarely developed, and nanomaterials are likely to be added to conventional chemical substances. However, there are no data on changes in the toxicity caused by interaction between nanomaterials and dissolved chemical substances. Thus, a trace amount of nano-zinc oxide, which has no effect on cell viability, was mixed with culture medium to examine the cytotoxicity level of Bis-GMA, which is routinely used as a dental monomer. As a result, the interaction between nano-zinc oxide and Bis-GMA slightly increased the cytotoxicity of Bis-GMA. Furthermore, we were clarified that the cytotoxicity levels slightly changed in the presence of a very small amount of nano titanium dioxide or nano zinc oxide compared with those in the absence of nanomaterials, but the changes were not marked. Those finding may contribute to future studies on the cytotoxicity of nanomaterials. Some of these discoveries may contribute to future research on the combined toxicity of nanomaterials.

Information related to the author
© 2020 Nano Biomedical Society
Previous article
feedback
Top