Inhibitory Effects of a Complex of Three Different Phytochemicals on                    the Growth of Five Types of Streptococcus                    Species

Tomoharu OKAMURA; Katsuhiro SUZUKI; Masumi MORI; Naoya UEMURA; Suguru DATEOKA; Hajime TABATA; Harumi ISONO; Jinhao CUI; Yukino HISANO; Takehiro YOSHIKANE; Chihoko IKEDA; Sho AOKI; Hayato OKA; Junichi FUJITA; Naoyuki MATSUMOTO; Kazuya TOMINAGA

doi:10.11344/nano.15.21

ORIGINAL ARTICLES

Inhibitory Effects of a Complex of Three Different Phytochemicals on the Growth of Five Types of Streptococcus Species

Tomoharu OKAMURA, Katsuhiro SUZUKI, Masumi MORI, Naoya UEMURA, Suguru DATEOKA, Hajime TABATA, Harumi ISONO, Jinhao CUI, Yukino HISANO, Takehiro YOSHIKANE, Chihoko IKEDA, Sho AOKI, Hayato OKA, Junichi FUJITA, Naoyuki MATSUMOTO, Kazuya TOMINAGA

Author information

Tomoharu OKAMURA
Department of Oral Pathology, School of Dentistry, Osaka Dental University, Osaka, Japan
Katsuhiro SUZUKI
Department of Oral Pathology, School of Dentistry, Osaka Dental University, Osaka, Japan
Masumi MORI
Department of Orthodontics, School of Dentistry, Osaka Dental University, Osaka, Japan
Naoya UEMURA
Department of Oral Implantology, School of Dentistry, Osaka Dental University, Osaka, Japan
Suguru DATEOKA
Department of Special Care Dentistry, School of Dentistry, Osaka Dental University, Osaka, Japan
Hajime TABATA
Department of Periodontology, School of Dentistry, Osaka Dental University, Osaka, Japan
Harumi ISONO
Department of Oral Pathology, School of Dentistry, Osaka Dental University, Osaka, Japan
Jinhao CUI
Department of Oral Pathology, School of Dentistry, Osaka Dental University, Osaka, Japan
Yukino HISANO
Department of Oral Pathology, School of Dentistry, Osaka Dental University, Osaka, Japan
Takehiro YOSHIKANE
Department of Oral Pathology, School of Dentistry, Osaka Dental University, Osaka, Japan
Chihoko IKEDA
Department of Oral Pathology, School of Dentistry, Osaka Dental University, Osaka, Japan
Sho AOKI
Department of Pediatric Dentistry, School of Dentistry, Osaka Dental University, Osaka, Japan
Hayato OKA
Department of English, School of Dentistry, Osaka Dental University, Osaka, Japan
Junichi FUJITA
Department of English, School of Dentistry, Osaka Dental University, Osaka, Japan
Naoyuki MATSUMOTO
Department of Orthodontics, School of Dentistry, Osaka Dental University, Osaka, Japan
Kazuya TOMINAGA
Department of Oral Pathology, School of Dentistry, Osaka Dental University, Osaka, Japan

Keywords: antibacterial test, colony growth inhibitor, early-occupying bacteria, streptococci, phytochemicals

JOURNAL OPEN ACCESS

2023 Volume 15 Issue 1 Pages 21-26

DOI https://doi.org/10.11344/nano.15.21

Details

Abstract

Bacterial attachment to tooth surfaces via acquired pellicles is important in the mechanism of caries development. Streptococci are the initial colonizers on the tooth surface. Dental plaque maturation occurs when late-established bacteria bind and grow on the outside of the early-established bacteria. Phytochemicals are part of the plant defense system, and a variety of antimicrobial components are known to exist. However, the effects of complexes containing multiple phytochemicals on the initial settlement of bacteria in dental plaque are not known.

In this study, we prepared a complex of three Phytochemicals (IP2). Then we investigated the inhibitory effects of a complex of three different phytochemicals on the growth of five types of early-occupying bacteria constituting dental plaque. As a result, there was a large inhibitory effect on the number of all colonies.

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