Nano Biomedicine
Online ISSN : 2185-4734
Print ISSN : 1883-5198
ISSN-L : 1883-5198
ORIGINAL ARTICLES
Modification of Composite Resin Surface with Carbon Nanotubes Enhances Cell Proliferation
Saori TANAKAHirofumi MIYAJIErika NISHIDAKana INOUESaori MIYATAAkihito KATOIzumi KANAYAMAShusuke MURAKAMIKohei KAWAMOTOBunshi FUGETSUToru TANAKAHiroko TAKITATadashi IIZUKAMasamitsu KAWANAMI
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2016 Volume 8 Issue 1 Pages 27-34

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Abstract

Composite resin (CR) is used in vivo as a root perforation sealer and as a retrograde obturation material following apicoectomy, but it does not possess adequate biocompatibility. Effective biological modification of the CR surface is thus needed to improve its biocompatibility. Carbon nanotubes (CNTs) are a type of nanocarbon material formed from cylindrical graphene sheets with a diameter of about 10 to 200 nm. CNTs have garnered attention for useful properties such as promoting cell adhesion and proliferation. The present study evaluated cell adhesion and proliferation on CR discs coated with CNTs. CR discs were coated by immersion in a dispersion of CNTs (Nanocyl NC7000, 9.5 nm diameter). The CNT coating was then observed with a scanning electron microscope (SEM) to investigate its surface properties. The effects of CNT coating were also investigated by conducting cell culture assay using osteoblasts. The coating process enabled CNTs to adhere to the resin surface, resulting in good adhesion and spreading of the osteoblasts that indicated a high level of cell proliferation. The study findings showed that coating the surface of CRs with CNTs improved their biocompatibility.

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© 2016 Nano Biomedical Society
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