Abstract
Effects of five environmental endocrine disruptors (environmental hormones) and analogous chemicals on mitosis were analyzed in the root-tip cells of Allium cepa L. Mitotic cell count decreased as the molar concentration of chemical solution increased. The chi-square test indicated significant difference between control and test solutions: 0.75 × 10-2 mg/ml 1-Naphthyl methylcarbamate, 0.03 mg/ ml S-Methyl N-(Methylcarbamoyloxy) thioacetimidate, 0.1 × 10-3 mg/ml 2,2-Bis(4-hydroxyphenyl)-propane, 0.25 × 10-1 mg/ml Di-2-ethylhexyl) phthalate, and 6.25 × 10-2 mg/ml Benzyl n-buthyl phthalate. Chromosome aberration, such as stickiness, attenuation, and chromosome breakage, was noted in almost all solutions. With regard to the chromosomes, remarkable declines in stainability were observed in all chemical samples of higher concentrations with the exception of 2,2-Bis(4-hyd roxyphenyl)-propane.
