Abstract
Hydro-gel of cross-linked poly (γ-glutanic acid) (γ-PGA) was synthesized by heating a aqueous solution of γ-PGA (pH 4~5.5) in the presence of a small amount of ethylene glycol diglycidyl ether (EGDE) as a cross-linker. Powder samples were obtained by freeze-drying the hydro-gels after neutralization with aqueous sodium bicarbonate solution or without neutralization. Water absorption ratio (weight (g) of absorbed water / weight of dry polymer (g)) of the cross-linked products obtained under the condition of [γ-PGA]/[EGDE]=1/0.05, pH 5.5, at 70 ℃ , for 4 h reached 1200. The obtained powdered samples may be applicable to inhibitors for body organ’s coalescence in surgical sites.
