Bitter Components from the Leaves of Isodon Species

Abstract

Constituents of the leaves of Isodon species have been examined. From I. longitubus KUDO, nodosin, lasiodin, isodocarpin and oridonin were isolated. From I. shikokianus HARA var. intermedius MURATA, a new bitter component, isodomedin, was isolated. From I. Kameba OKUYAMA, kamebanin and mebadonin, from I. inflexus KUDO, inflexin, from I. umbrosus HARA, umbrosin and from I. effusus HARA, effusin were isolated as new components. Parts of structures have been assigned to these new compounds from spectroscopic evidence.