Synthesis of Acid Chiorides by the Reaction of Carboxylic Acids with Sulfur Monochloride in the Presence of lron-salt Catalyst

Abstract

Sulfur monochloride and carboxylic acids do not reqct without catalyst, but react, easily in the presence of catalyst such as reduced iron powder, ferrous chloride, sulfate, oxqlate and formate, and ferric chlQride, sulphate and acetate giving acid chlorides. Arematic mpno- and dicarboxylic acids (isophthalic and terephtha1ic acids, with exception of phthalic acid)'and lower fatty acids produced acid chlorides in geod yields. Adipic aid, aliphatic dicarbexylic acid, produced small quantity of acid chloride in the presence of ferric acetate enly, . but in the presence of ferric acetate and pyridine the yield of acid chloride rose to about 5Q%.