The Reaction of Urea, Thiourea and S-Ethylisothiourea with Methyl Acrylate

Abstract

5, 6-Dihydro-2, 4-dihydroxy-pyrimidine C 1 D, 5, 6-dihydro-4-hydroxy-2-mercapto-pyrimidine C 3 J and 5, 6-dihydro-2-ethylmercapto-4-hydroxy-pyrimidine C 4 J were prepared by the reaction of urea, thiourea and S-ethylisothiourea with methyl acrylate, respectively.2-Arylamino-5, 6- dihydro-4-hydroxy-pyrimidines [5 ad] were obtained by the reaction of C 4J with aryl amines (aniline, p-toluidine, p-anisidine and p-chloroaniline) 8-Arylguanidinopropionic acids C6 aclip were obtained by the hydrolysis of [5 ad].