Amination of 2-Naphthol-8-sulfonate and m-Xylene-5-sulfonatet

Abstract

1-Amino-7-naphthol and 3, 5-xylidine were prepared by amination of potassium 2-naphthol8-sulfonate and m-xylene-5-sulfonate, respectively.
Potassium 2-naphthol-8-sulfonate was allowed to react with sodium amide in liquid ammonia at 160°C for 16 hours to give 1-amino-7-naphthol in a 84.5% yield, whereas sodium 2-naphthol6-sulfonate did not undergo the amination under these conditions.3, 5-Xylidine was obtained by the amination of potassium m-xylene-5-sulfonate at 155°C for 9 hours in a 82.7% yield.