Synthesis and Reactions of 1-Methyl-4, 5-imidazoledicarbonyl Dichloride

Abstract

1-Methyl-4, 5-imidazole dicarbonyl dichloride (1) was obtained in a high yield by the Teaction of 1-methyl-4, 5-imidazole-dicarboxylic acid with an excess of thionyl chloride or with a stoichiometric amount of phosphorus pentachloride. (1) reacted with methanol, phenel, methylamine, aniline and several diamines to give the corresponding esters, amides and polyamides. Further reaction of (1) with an excess pf phosphorus pentachloride gave 1-methyl-4-triehleromethyl-5-imidazole carbonyl chloride.