Hydration of r and 8-Cadinenes with Chloroacetic Acids

Abstract

The hydration of r-cadinene [ 1 ] and 8-cadinene [ 2] with mono-, di and trichloroacetic acids was investigated and five products were isolated by means of distillation and gas chromatography.
The structures of 1(10)-cadinen-4 α-ol [ 3 ], 4-cadinen-10 α-ol (T-cadinol) [ 4 ], 1(10)-cadinen 4 β-ol. [ 5 ], 4-cadinen-10 β-ol (α-cadinol) [ 6] and 10(15)-cadinen-4-ol [ 7 ] were assigned on the basis of their physical constants, IR and NMR spectra.
Hydration of [1] yield [6 ] as a major product, while [2 ] yielded mainly [3].