Preparation of 6-(Normal alkyl)-4-chloropheno1-2-sulfonates, and Their Surface Active and Antimicrobial Properties

Abstract

Five 6-(normal alkyl)-4-chlorophenol-2-surfonates (alkyl; n-C₆H₁₃, n-C₈H₁₇, n-C₁₀H₂₁, n-C₁₂H₂₅ and n-C₁₄H₂₉) were synthesized and identified by elemental and spectroscopic analyses. Surface active and antimicrobial properties of these compounds were investigated. The results are as follows:
1) Surface activity (surface tension, emulsifying, dispersing, and solubilizing power)increased with increasing alkyl-chain length up to n-C₁₂H₂₅ and then decreased in the n-C₁₄H₂₉ drivative.
2) These sulfonates were screened for antimicrobial properties with gram-positive and gram-negative bacteria, and fungi. It was found that the n-C₁₀H₂₁ derivative had activity comparable to that of the control sample PCP.