Synthesis of α, β-Unsaturated Carboxamides Using Dialkyltelluronium Carbamoylmethylide

Abstract

Reaction of dibutyltelluronium (isobutylcarbamoyl)methylide with aldehydes gave α, β-unsaturated carboxamides with high E-selectivity and good yields. When reacted with trans-2-octenal, this reagent afforded pellitorine ((2 E, 4 E)-N-isobutyl-2, 4-dodecadienamide)in 71% isolated yield.