Oxygen Exchange between Polymerized Liposome-embedded Lipid-heme and Human Red Blood Cell

Abstract

A polymerized liposome-embedded lipid-heme (liposome/li pid-heme) solution was mixed with a red blood cell suspension or myoglobin solution. The oxygen exchange between the two media was measured by visible spectroscopy. It was found that oxygen was provided from liposome/lipid-heme to red blood cell or myoglobin. The exchange percentages agreed with the curves calculated from the oxygen-binding versus-dissociation relationship.