Comparison of Hydrogen Isotope Exchange Reactions between HTO Vapor and the Sodium Salts of o-, m-, and p-Aminobenzoic Acid

Abstract

Hydrogen isotope exchange raction between HTO vapor and one of the sodium salts of a-, m-, and p-aminobenzoic acid (solid) was observed at 50-80°C. The acidity (acidity based on kinetic logic) for the materials at each temperatur has been obtained with the A"-McKay plots based on the respective data obtained. The followings have been clarified by comparing these acidities (and the acidities obtained previously).1) The acidity of aromatic amines can be expressed in terms of the acidity based on kinetic logic.2) The reactivity of aromatic amine is strongly affected by both I-effect and R-effect.3) It can be deduced that aromatic amines are more reactive than aliphatic amines.