Investigation of Quantitative Structure Antimicrobial Activity Relationship of 2-Arylthio-N-methylmaleimidest

Abstract

Quantitative structure activity relationship of 2-arylthio-N-methylmaleimides against B. subtilis was examined, and the effects of substituents on benzene ring of those compounds were correlated with bacteriostatic activity. For p-substituted compounds, following correlative equation was introduced Also for o-subsituted compounds, following correlative equation was introduced