Abstract
Synopsis. fac(+)-[Cr(L-isoleu)(L-leu)2]⋅ 3H2O and fac(-)-[Cr(D-isoleu)(L-leu)2]⋅ 3H2O were prepared by a method, in which [Cr (L-leu)2(NCS) (CH2)] (leu=leucinato) was heated with L- and D-isoleucine, respectively, in ethanol solution (75 ° C, 5 h). Also, fac(+)-[Cr (L-isoleu)(L-leu)2]V 2H2O and fac(-)-[Cr(D-isoleu)(L-leu)2]⋅ 2H2O were obtained from the filtrate independent of the standing temperatures (5-55 ° C) at 10 days. In the case of DL-isoleucine, the diastereomeric mixture of fac(-1-)-[Cr(L-isoleu)(L-leu)2]⋅ 3H2O and fac (-)-[Cr(D-isoleu)(L-leu)2]⋅ 3H2O were prepared during heating. While, fac()-[Cr(D-isoleu)(L-leu)2]⋅ 2H2O (standing temperature 5 or 25° C) and fac(±)-[Cr(L-isoleu) (L-leu)2]⋅ 2H2O (standing temperature 40 or 55 ° C) were obtained from the filtrate. By using thi s method, the optical resolution of DL-isoleucine was suggested.
