Abstract
In order to reinvestigate the interpretation of the data reported with respect to 1H-NMR spectra of la-hydroxyvitamin D2 (1a) and (24S) -1α -hydroxyvitamin D2 (1b), 1b and 28-deuteriated vitamin D2derivatives (1c) were synthesized efficiently via C-22 aldehyde (2). Both 1a and 1b have been examined by 1H-NMRs pectroscopy to clarify that 1) the 1H-NMRs ignal assignments of the 21-H and 28-H were reverse in previous data, 2) two doublets (J=6.6 Hz) due to the 21-H of 1a and 1b are clearly observed at δ =1.017 and 1.009, respectively.
