Abietane-type Diterpenoids from the Fruit of Vitex rotundifolia L. fil.

Abstract

Two new diterpenes 1 and 2 were isolated from the fruit of Vitex rotundifolia L. fil. These compounds were determined as abieta-9 (11), 12-diene and abietane 9 (11): 12 (13)-di-α-epoxide, respectively. Structural determination of 1 was made by the connection of spectroscopic data and the results that 1afforded known αγ-abietatriene (3) by air oxidation. That of 2 was also made by the comparison of spectroscopic data of the MCPBA oxidation products 2, 4, and 5 of 1 and by the analysis of the epoxide ring opening reaction product of 4.