Abstract
Objective To examine the relationship between the serum level of iron and that of CRP within its normal range of 0-5 mg/l.
Methods A cross-sectional study involving 7250 male employees who underwent an annual health checkup was conducted. Information regarding current medications and lifestyle habits was obtained using a self-reported questionnaire.
Results The subjects were divided into 6 groups based on the serum level of CRP in the range 0 to 5 mg/l and the mean values were compared among the groups. The mean level of iron decreased from 21.8 mmol/l to 17.2 mmol/l as the CRP level increased from 0 mg/l to 5 mg/l. However, there was no change in the level of Hb or the erythrocyte mean cell volume. Similar results were obtained when values were adjusted for the age, BMI, smoking, alcohol consumption, and physical activity.
Conclusion These results indicated a negative association between the serum level of iron and that of CRP within its normal range. (Ningen Dock 2010; 24: 39-41)
