Appendectomy Rates in Ningen Dock Subject Histories and Effect of Appendectomy on Dock Data

Abstract

Objective: We investigated whether subjects with appendectomy in their history exhibited certain characteristics based on Ningen Dock results.
Methods: Our subjects were 10,093 men and 3,087 women who had undergone an annual health check-up. Exclusion criteria included medications for diabetes, hypertension, dyslipidemia, and hyperuricemia, and past history of cardio- and cerebrovascular diseases.
Results: The appendectomy rates in men and women were 6.6 and 5.6% overall and 2.5 and 2.7%, 4.0 and 4.8%, 6.6 and 6.6%, and 9.3 and 9.7%, for those in their twenties, thirties, forties, and fifties, respectively. Since there was a significant difference in average age between subjects with appendectomy in their history and those without, the Ningen Dock results of the 2 groups were compared after being adjusted for age. Total globulin was lower (men: 2.59 vs. 2.65 mg/dL (p=0.012), (women: 2.66 vs. 2.73 mg/dL (p=0.070)) in subjects who had undergone appendectomy, but there was no difference in blood pressure, pulse rate, blood cell count, hepatic and biliary enzymes, serum lipids, renal function, total protein, albumin, or CRP.
Conclusions: These findings suggest that appendectomy might affect immune function because total globulin includes immunoglobulin.